Apex Systems Looking for Scientist/Sr. Scientist, Oligonucleotide Chemistry at Newton, MA Full Time

Job Description:

Scientist/Sr. Scientist, Oligonucleotide Chemistry 1288403

Job Scope & Purpose:

Our Newton/Watertown based client is seeking a candidate and exceptional individual to join their growing team as Scientist/Sr. Scientist. The candidate will develop synthesis and purification of modified oligonucleotides (ASO, siRNA) for drug discovery programs. Successful candidates will have significant experience with solid phase chemical synthesis (oligonucleotide or peptide), conjugation, HPLC purification, and LC-MS analysis. Expertise operating oligonucleotide synthesis equipment and HPLC is required; experience using LCMS is preferred. Ability to thrive in a team, goal driven and time-sensitive environment, are key attributes. Please apply if you are ready to advance your career!

Responsibilities:

• Development of techniques and performing automated synthesis, cleavage, deprotection, purification, analysis and packaging of oligonucleotides, including heavily modified oligonucleotides.
• Monitoring, troubleshooting, maintenance, repair equipment or engage repair services of the oligonucleotide synthesizer, HPLC machines and benchtop equipment to ensure consistent and reliable oligonucleotide production.
• Critical evaluation and optimization of the processes to improve synthesis yield, purity and timelines for production of modified oligonucleotides
• Manage ordering and organization of chemicals and supplies necessary for oligonucleotide synthesis
• Supervise curation and maintenance of the inventory of synthesized oligonucleotides

Qualifications:

• PhD in Oligonucleotide-related area of Chemistry, Chemical/Process Engineering or Biochemistry with or w/o experience in an industry setting or Master’s Degree with 5-7 years’ experience in an industry setting,
• self-motivated with the ability to work in a fast-paced environment
• Work authorization in the USA is required.
• Strong analytical skills
• Strong problem-solving skills for developing creative, innovative solutions, and meeting project objectives.
• Extensive experience in driving and supporting external teams at CRO’s.
• Proven track record of scientific contributions to projects, including co-inventorship on patents.
• (Co)-authorship on publications and presentations is required.
• Strong interpersonal skills.
• Scientific creativity, independent thought and decision-making ability.
• Outstanding written, verbal and presentations skills.
• Exceptional problem-solving skills.

About Stratacuity:

Whether you are seeking a career change or simply interested in becoming part of our network, you will appreciate the ethics guiding each Stratacuity team member. We build lasting relationships with exceptional biopharmaceutical talent and take great care to protect your personal information. Upon receiving your inquiry, you may be directly contacted by a Stratacuity team member to discuss your career goals. We will not share your information with anyone without your direct prior consent.

PROVEN SCIENTIFIC PLACEMENT™

Stratacuity is an Equal Employment Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, age, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law. Stratacuity will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact us.

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EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at or